发表文献_发表文献_应世生物_FAK抑制剂IN10018

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Targeting FAK improves the tumor uptake of antibody-drug conjugates to strengthen the anti-cancer responses

○ Targeting FAK improves the tumor uptake of antibody-drug conjugates to strengthen the anti-cancer responses

发布时间 2024-12-05

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Prospects of focal adhesion kinase inhibitors as a cancer therapy in preclinical and early phase study

○ Prospects of focal adhesion kinase inhibitors as a cancer therapy in preclinical and early phase study

发布时间 2024-06-01

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Targeting focal adhesion kinase boosts immune response in KRAS/LKB1 co-mutated lung adenocarcinoma via remodeling the tumor microenvironment

○ Targeting focal adhesion kinase boosts immune response in KRAS/LKB1 co-mutated lung adenocarcinoma via remodeling the tumor microenvironment

发布时间 2024-01-30

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Simultaneous inhibition of FAK and ROS1 synergistically repressed triple-negative breast cancer by upregulating p53 signalling

○ Simultaneous inhibition of FAK and ROS1 synergistically repressed triple-negative breast cancer by upregulating p53 signalling

发布时间 2024-01-25

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Synergism of FAK and ROS1 inhibitors in the treatment of CDH1-deficient cancers mediated by FAK-YAP signaling

○ Synergism of FAK and ROS1 inhibitors in the treatment of CDH1-deficient cancers mediated by FAK-YAP signaling

发布时间 2023-05-15

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A phase Ib study of IN10018 in combination with pegylated liposomal doxorubicin (PLD) in patients with platinum-resistant ovarian cancer.

○ A phase Ib study of IN10018 in combination with pegylated liposomal doxorubicin (PLD) in patients with platinum-resistant ovarian cancer.

发布时间 2022-06-07

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Focal adhesion kinase inhibitors, a heavy punch to cancer

○ Focal adhesion kinase inhibitors, a heavy punch to cancer

发布时间 2021-11-25

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Inhibition of focal adhesion kinase enhances antitumor response of radiation therapy in pancreatic cancer through CD8+ T cells

○ Inhibition of focal adhesion kinase enhances antitumor response of radiation therapy in pancreatic cancer through CD8+ T cells

发布时间 2021-08-08

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Focal Adhesion Kinase (FAK) Inhibition Synergizes with KRAS G12C Inhibitors in Treating Cancer through the Regulation of the FAK–YAP Signaling

○ Focal Adhesion Kinase (FAK) Inhibition Synergizes with KRAS G12C Inhibitors in Treating Cancer through the Regulation of the FAK–YAP Signaling

发布时间 2021-02-15

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